The
Daily
Fix
15-12-9-6-3 reps:
Beef Stroganoff over Mashed Cauliflower
Raise standards for preclinical cancer research
Thrusters
Knees-to-elbows
Snatches
Knees-to-elbows
Hearty ground beef simmered in a rich, creamy herb-infused sauce, served over buttery mashed cauliflower.
Glenn Begley and Lee Ellis propose how methods, publications and incentives must change if patients are to benefit.
Men use a 75-lb barbell.
Women use a 55-lb barbell.
Knees-to-elbows are strict.
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Ingredients
For the Stroganoff:
6 oz ground beef
½ cup beef bone broth
¼ cup heavy cream
1 Tbsp cream cheese
½ tsp onion powder
½ tsp garlic powder
¼ tsp smoked paprika
½ tsp dried thyme
Salt and pepper, to taste
½ Tbsp butter
For the Mashed Cauliflower:
1 cup cauliflower florets
2 Tbsp heavy cream
1 Tbsp butter
Salt and pepper, to taste
Macronutrients
Protein: 38g
Fat: 48g
Carbs: 8g
Preparation
In a skillet over medium-high heat, lightly brown the ground beef (6 oz), breaking it up with a spatula as it cooks.
Once the beef (6 oz) is mostly browned, stir in beef bone broth (½ cup) and heavy cream (¼ cup). Add cream cheese (1 Tbsp), onion powder (½ tsp), garlic powder (½ tsp), smoked paprika (¼ tsp), dried thyme (½ tsp), and a generous pinch of salt and pepper (to taste).
Bring the mixture to a simmer and cook for 5–7 minutes, stirring occasionally, until the sauce reduces and thickens to a creamy consistency. Stir in butter (½ Tbsp) for added richness, if desired. Taste and adjust seasoning.
Meanwhile, steam or boil cauliflower florets (1 cup) until fork-tender. Drain and mash with heavy cream (2 Tbsp), butter (1 Tbsp), salt, and pepper (to taste) until smooth and creamy.
To serve, spoon the creamy beef stroganoff (entire mixture) over a bed of mashed cauliflower (entire mixture). Garnish with fresh parsley if you like.
This 2012 article discusses systemic issues in the field of preclinical cancer research, focusing on the lack of rigor and in ability to reproduce results in published studies. Researchers from Amgen Corp looked at 53 published studies and tried to replicate their findings. They were only able to reproduce six of the 53 experimental results. This poor ability to replicate the work points to massive problems in oncology and hematology research. The 53 papers had been previously thought to have validated results and had been relied on for subsequent research.
TUESDAY 250603