As everyone knows, a placebo is an inactive ‘sugar’ pill. Except when it isn’t. Which is almost always.

Dr. Drew and Emily call attention to the flaws in the current state of modern science. Emily and Drew discuss the Dana-Farber scandal, the cost/benefit of going to college, the do-or-die culture in science, and the lack of curiosity among journalists.

William Briggs explains the basics of calculating probability, which pieces of the calculation are subjective, and how the results can influence beliefs and actions.

Breaking down composite endpoints to their component parts.

In this video Emily explains the difference between a Bayesian approach and a frequentist approach to analyzing statistics. A Bayesian analysis looks at prior probabilities combined with data to determine the probability that the hypothesis is true. A frequentist analysis compares the hypothesis to the null-hypothesis, a yes/no approach, to determine if the data could support the null-hypothesis. It then ranks the data with a P-value, but it actually says nothing about the hypothesis being true.

Harvard medical school 'research-integrity officer' was co-author of studies in question.

Explaining how a clinical trial can report success – when there is none.

In February of 2023 Dr. Kendrick spoke at BSI’s event in Phoenix, AZ. Malcom’s presentation recaps the history of the diet-heart hypothesis, the supposed link between cholesterol and cardiovascular death, and how drug companies have fooled doctors into prescribing medications that are harming patients rather than helping them.

Scientific misconduct is ever becoming more recognized as a problem, yet what exactly constitutes misconduct varies by source.