Over the years there have been many risk calculators for cardiovascular disease. Which of them works best? The answer is… none of them.

Dr. Malcolm Kendrick and Zoë Harcombe PhD received a judgement in their favor yesterday in a London court. Kendrick and Harbombe had filed a libel suit against Associated Newspapers and a journalist who published defamatory articles about them due to their position on the effectiveness of statins.

If we can't trust study results, and we can't repeat studies, where do we stand?

Malcolm explains how trials become unblinded, either officially or through indicators in biomarkers.

Malcolm elaborates on the power to manipulate studies when placebos are not benign.

William Briggs rebuts at a recent publication that claimed intermittent fasting increases risk of cardiovascular death.

As everyone knows, a placebo is an inactive ‘sugar’ pill. Except when it isn’t. Which is almost always.

Breaking down composite endpoints to their component parts.

Explaining how a clinical trial can report success – when there is none.