This month we will dive deeper into hereditary cancer genes.
Last month we explored Bob Kaplan’s new paper on the nature of hereditary cancer syndromes. His paper makes a case for the metabolic theory of cancer as it relates to the precise mutations many cite as proof for the somatic mutation theory.
But have you ever wondered what functions they perform under normal conditions or even during exercise?
Join us to find out.
Featured papers:
- Kaplan et al (2025): Hereditary cancer syndromes linked to oxidative phosphorylation insufficiency
- Nemkov et al (2023): Metabolic Signatures of Performance in Elite World Tour Professional Male Cyclists
- Tarpey et al (2021): Skeletal Muscle Function Is Dependent Upon BRCA1 to Maintain Genomic Stability
- Park et al (2009): p53 improves aerobic exercise capacity and augments skeletal muscle mitochondrial DNA content
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