Brad Jones
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Malcolm Kendrick wrote a new post
1 week, 4 days agoResearch Manipulation Part VIII: Placebos, Trial Blinding, and Biomarkers
Malcolm explains how trials become unblinded, either officially or through indicators in biomarkers.
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Malcolm Kendrick wrote a new post
1 month agoResearch Manipulation Part VII: If placebos are not true placebos…then what
Malcolm elaborates on the power to manipulate studies when placebos are not benign.
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Malcolm Kendrick wrote a new post
2 months agoResearch Manipulation Part VI: Placebos – the (not) nothing pill
As everyone knows, a placebo is an inactive ‘sugar’ pill. Except when it isn’t. Which is almost always.
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Emily Kaplan wrote a new post
2 months, 2 weeks agoThe Dr. Drew Podcast with Emily Kaplan
Dr. Drew and Emily call attention to the flaws in the current state of modern science. Emily and Drew discuss the Dana-Farber scandal, the cost/benefit of going to college, the do-or-die culture in science, and…
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Emily Kaplan wrote a new post
2 months, 3 weeks agoLive with Ken Berry, MD
On February 27th, BSI Co-Founder and CEO Emily Kaplan was interviewed by Dr. Ken Berry. During the livestream, the two […]
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Emily Kaplan wrote a new post
2 months, 4 weeks agoThe B FIT Podcast w/ Connor Murphy
On February 15th, Co-founder and CEO of The Broken Science Initiative, Emily Kaplan, went onto the B FIT Podcast with […]
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Malcolm Kendrick wrote a new post
2 months, 4 weeks agoResearch Manipulation Part V: Looking Even Closer
Breaking down composite endpoints to their component parts.
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Emily Kaplan wrote a new post
3 months agoBayesian Vs. Frequentist Statistics
In this video Emily explains the difference between a Bayesian approach and a frequentist approach to analyzing statistics. A Bayesian analysis looks at prior probabilities combined with data to determine the…
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Malcolm Kendrick wrote a new post
3 months, 2 weeks agoResearch Manipulation Part IV: Falsely Reporting Success
Explaining how a clinical trial can report success – when there is none.
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Emily Kaplan wrote a new post
4 months agoP-Values Explained
Simply put, a p-value is a measure of the likelihood that the results of a study are due to the hypothesis, and not simply a result of chance. It compares the “null hypothesis,” the idea that the thing being stu…
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Malcolm Kendrick wrote a new post
4 months, 1 week agoResearch Manipulation Part III: Deliberate Obfuscation
In this edition Malcolm explains how study results can be carefully worded, to imply results that are actually contrary to data.
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Emily Kaplan wrote a new post
4 months, 2 weeks agoAsk Dr. Drew: Is Long-Term Statin Use Accelerating Heart Failure?
On his podcast, Emily and Dr. Drew talked at length about the overuse of statins to treat coronary heart disease.
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Malcolm Kendrick wrote a new post
5 months agoResearch Manipulation Part II: Surrogate end-points
Using surrogate end-points for clinical trials represents a massive boost for pharmaceutical company profits. So, they work hard, behind the scenes, to ensure that this happens
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Malcolm Kendrick wrote a new post
5 months, 1 week agoResearch Manipulation Part I: Setting Up The Trick
Much planning and setup is needed to convince the world medical treatments are effective, or even necessary in the first place.
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Emily Kaplan wrote a new post
5 months, 3 weeks agoThe Purpose and Limitations of Observational Studies
Emily explains the strengths, weaknesses, and ways to interpret observational studies. These types of studies can be useful for identifying links between things, and then generating hypotheses. However, the…
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Emily Kaplan wrote a new post
5 months, 4 weeks agoUnderstanding All-Cause Mortality
In this next video, BSI’s Emily Kaplan explains all-cause mortality, and how it should be included when considering any medical treatment.
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Emily Kaplan wrote a new post
6 months agoUnderstanding All-Cause Mortality
In this video Emily explains all-cause mortality, and how it impacts decision making for medical intervention.
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Emily Kaplan wrote a new post
6 months agoUnderstanding Medical Tests
In this video, Emily explains how to understand medical tests. She dives into both sensitivity and specificity of testing.
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Emily Kaplan wrote a new post
6 months agoInduction Vs. Deduction
In this next part, Emily breaks down the difference between induction and deduction.
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