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Indian Butter Chicken

Brain Energy: The Metabolic Theory of Mental Illness

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Rest day

Tender chicken simmered in a rich, creamy, and spiced tomato-butter sauce.

A growing body of research suggests that many mental disorders may stem from metabolic dysfunction in the brain.

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The
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Enjoy the recovery time, or make-up anything you missed from last week.

Ingredients

For the Chicken Marinade:
1 ½ lbs chicken thighs or breasts, cut into bite-sized pieces
½ cup full-fat Greek yogurt
1 Tbsp lemon juice
1 tsp ground cumin
1 tsp garam masala
1 tsp smoked paprika
½ tsp turmeric
½ tsp salt

For the Butter Sauce:
3 Tbsp butter or tallow
2 cloves garlic, minced
1 Tbsp grated fresh ginger
1 cup tomato puree (no added sugar)
1 tsp ground cumin
1 tsp garam masala
½ tsp chili powder (adjust for spice preference)
¾ cup heavy cream
Salt and black pepper, to taste
1 Tbsp chopped cilantro (for garnish)

Macronutrients
(per serving, serves 4)

Protein: 40g
Fat: 36g
Carbs: 7g

Preparation

In a bowl, combine chicken, yogurt, lemon juice, cumin, garam masala, paprika, turmeric, and salt. Mix well, cover, and marinate at least 30 minutes or up to overnight in the refrigerator.

Heat 2 Tbsp butter or tallow in a skillet over medium-high heat. Add the chicken and cook for 4–5 minutes until browned on all sides (it doesn’t need to be fully cooked yet). Remove and set aside.

In the same skillet, melt the remaining 1 Tbsp butter. Add garlic and ginger, cooking for 30 seconds until fragrant.

Stir in tomato puree, cumin, garam masala, chili powder, salt, and pepper. Simmer 3–4 minutes until slightly thickened.

Add the chicken back into the pan and pour in heavy cream. Stir to combine and simmer for 8–10 minutes, until the sauce is rich and the chicken is cooked through.

Taste and adjust seasoning with salt or spice as needed.

Garnish with chopped cilantro and serve hot — ideal with cauliflower rice or sautéed greens for a low-carb pairing.

In this article, Harvard psychiatrist Christopher Palmer proposes that mental illnesses may fundamentally be metabolic disorders of the brain. Drawing on research from neuroscience, genetics, and metabolism, Palmer argues that dysfunction in cellular energy systems—particularly in mitochondria—can help explain the wide range of factors associated with mental illness, including neurotransmitters, hormones, inflammation, and gene expression. Viewing mental disorders through a metabolic lens offers a unifying framework that connects mental and physical health and may help explain why many current treatments fail to achieve lasting remission. The model also highlights the therapeutic potential of metabolic interventions such as diet, exercise, sleep, stress management, and reducing substance use. By focusing on brain energy metabolism, this perspective suggests new avenues for treating psychiatric disorders while reinforcing the central role of cellular energy and mitochondrial function in brain health.

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COMMENTS

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RACHEL STEADMAN March 27, 2026 | 03:33 EST
So good! ! Genuinely one of the best curries I've ever made.
Dusty Russell - MetFix Blueprint April 07, 2026 | 18:51 EST
Agreed! Great recipe, very delicious.
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