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From the bodybuilder paradox – why those who put on muscle easy are so easily deluded about those who put on fat – to the infamous ob/ob (obese) mouse that reshaped our understanding of fat and hunger, this discussion uncovers how scientific dogma and misplaced faith in “calories in, calories out” derailed metabolic science. Together, the panel explores how leptin, fuel partitioning, and flawed interpretation have kept us stuck in a broken model of health, and what it takes to rewrite it.
Each episode, your hosts Karen and Mia cut through the noise with sharp commentary, headline debunking, expert interviews, and practical metabolic advice you won’t hear anywhere else. From retracted “miracle” studies to Reddit-fueled health myths, we’re setting the record straight.
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recent posts
Inside Dave Feldman’s KetoCa study and the questions surrounding its data, analysis, and quality control
Paradigm Shifts, Entrenched Thinking, and the Future of Medicine
A new paper proposes a single ratio, read off a fingerprick, that tells you where your metabolism is headed. It started in a cancer clinic. Its authors think it belongs in every MetFix affiliate.
